Reconstructing Evolution: New Mathematical and Computational Advances Olivier Gascuel

ISBN: 9781281149114

Published: January 10th 2010

ebook

318 pages


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Reconstructing Evolution: New Mathematical and Computational Advances  by  Olivier Gascuel

Reconstructing Evolution: New Mathematical and Computational Advances by Olivier Gascuel
January 10th 2010 | ebook | PDF, EPUB, FB2, DjVu, talking book, mp3, ZIP | 318 pages | ISBN: 9781281149114 | 6.23 Mb

Evolution is a complex process, acting at multiple scales, from DNA sequences and proteins to populations of species. Understanding and reconstructing evolution is of major importance in numerous subfields of biology. For example, phylogenetics andMoreEvolution is a complex process, acting at multiple scales, from DNA sequences and proteins to populations of species. Understanding and reconstructing evolution is of major importance in numerous subfields of biology. For example, phylogenetics and sequence evolution is central to comparative genomics, attempts to decipher genomes, and molecular epidemiology.

Phylogenetics is also the focal point of large-scale international biodiversity assessment initiatives such as the Tree of Life project, which aims to build the evolutionary tree for all extant species. Since the pioneering work in phylogenetics in the 1960s, models have become increasingly sophisticated to account for the inherent complexity of evolution. They rely heavily on mathematics and aim at modelling and analyzing biological phenomena such as horizontal gene transfer, heterogeneity of mutation, and speciation and extinction processes.

This book presents these recent models, their biological relevance, their mathematical basis, their properties, and the algorithms to infer them from data.



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